The U.S. Department of State has issued a global caution advisory for American citizens traveling or residing abroad, citing heightened tensions in the Middle East following an escalation in the Israel–Iran conflict.

In a statement released on June 22, the Department urged U.S. nationals to remain vigilant amid disruptions to transportation and air travel across the region. It warned of potential demonstrations targeting American interests worldwide, Meduza reported on June 23.

While the State Department’s alert did not specifically mention recent U.S. strikes on Iran’s nuclear facilities, the Department of Homeland Security (DHS) pointed to an increased risk of domestic threats.

DHS reportedly noted that the ongoing conflict could radicalize violent extremists within the United States, especially if Iranian religious leaders call for retaliation against Washington’s actions.

The agency also warned of potential cyberattacks from Iran and risks to American officials whom Tehran continues to hold responsible for the 2020 killing of General Qassem Soleimani.

The DHS advisory, which remains in effect from June 22 to September 22, was released shortly after the U.S. military reportedly carried out strikes on Iranian nuclear sites in Fordow, Natanz, and Isfahan.  While the Pentagon has said it is still assessing the impact of the operation, former President

Donald Trump claimed that all three targets were successfully destroyed.

Iran has yet to officially confirm any of the reported damage, Meduza said, noting that according to NBC News, U.S. officials are preparing for a potential retaliatory response from Tehran.